PUBLICATIONS

Recent Publications

September 2020 PLOS computational bio.PN

~~Models of SIV rebound after treatment interruption that involve multiple reactivation events~~

PLOS Computational Biology (October 1, 2020)

Christiaan H. Van Dorp, Jessica M. Conway, Dan H. Barouch, James B. Whitney, Alan S. Perelson

~~A Direct-Acting Antiviral Drug Abrogates Viremia in Zika Virus-Infected Rhesus Macaques~~

Sci Transl Med. 2020; 12(547)

So-Yon Lim, Christa E Osuna, Katharine Best, Ray Taylor, Elsa Chen, Gyeol Yoon, Jessica L Kublin, Dane Schalk, Nancy Schultz-Darken, Saverio Capuano, David Safronetz, Ma Luo, Steve MacLennan, Amanda Mathis, Yarlagadda S Babu, William P Sheridan, Alan S Perelson, James B Whitney.

~~Prevention of SIVmac251 reservoir seeding in rhesus monkeys by early antiretroviral therapy~~

Nature Communications Vol. 9, Article number: 5429 (2018)

James B. Whitney, So-Yon Lim, Christa E. Osuna, Jessica L. Kublin, Elsa Chen, Gyeol Yoon, Po-Ting Liu, Peter Abbink, Erica N. Borducci, Alison Hill, Mark G. Lewis, Romas Geleziunas, Merlin L. Robb, Nelson L. Michael & Dan H. Barouch

~~Evidence that CD32a does not mark the HIV-1 latent reservoir~~

Nature 561 (7723): E20-E28 (19 September 2018)

Christa E. Osuna, So-Yon Lim, Jessica L. Kublin, Richard Apps, Elsa Chen, Talia M. Mota, Szu-Han Huang, Yanqin Ren, Nathaniel D. Bachtel, Athe M. Tsibris, Margaret E. Ackerman, R. Brad Jones, Douglas F. Nixon & James B. Whitney

~~TLR7 agonists induce transient viremia and reduce the viral reservoir in SIV-infected rhesus macaques on antiretroviral therapy~~

Sci Transl Med. 2018 May 2;10(439)

Lim SY, Osuna CE, Hraber PT, Hesselgesser J, Gerold JM, Barnes TL, Sanisetty S, Seaman MS, Lewis MG, Geleziunas R, Miller MD, Cihlar T, Lee WA, Hill AL, Whitney JB.

~~Nonhuman Primate Models of Zika Virus Infection, Immunity, and Therapeutic Development~~

Infect Dis. 2017 Dec 16;216(suppl_10):S928-S934

Osuna CE, Whitney JB.

~~Zika plasma viral dynamics in nonhuman primates provides insights into early infection and antiviral strategies.~~

Proc Natl Acad Sci U S A. 114(33):8847-8852 (August 15 2017)

Best K, Guedj J, Madelain V, de Lamballerie X, Lim SY, Osuna CE, Whitney JB, Perelson AS.

~~Zika viral dynamics and shedding in rhesus and cynomolgus macaques~~

Nature Medicine 22, 1448–1455 (2016)

Christa E Osuna, So-Yon Lim, Claire Deleage, Bryan D Griffin, Derek Stein, Lukas T Schroeder, Robert Omange, Katharine Best, Ma Luo, Peter T Hraber, Hanne Andersen-Elyard, Erwing Fabian Cardozo Ojeda, Scott Huang, Dana L Vanlandingham, Stephen Higgs, Alan S Perelson, Jacob D Estes, David Safronetz, Mark G Lewis & James B Whitney

~~Rapid seeding of the viral reservoir prior to SIV viraemia in rhesus monkeys~~

Nature 512, 74–77 (07 August 2014)

James B. Whitney, Alison L. Hill, Srisowmya Sanisetty, Pablo Penaloza-MacMaster, Jinyan Liu, Mayuri Shett, Lily Parenteau, Crystal Cabral, Jennifer Shields, Stephen Blackmore, Jeffrey Y. Smith, Amanda L. Brinkman, Lauren E. Peter, Sheeba I. Mathew, Kaitlin M. Smith, Erica N. Borducchi, Daniel I. S. Rosenbloom, Mark G. Lewis, Jillian Hattersley, Bei Li, Joseph Hesselgesser, Romas Geleziunas, Merlin L. Robb, Jerome H. Kim, Nelson L. Michael & Dan H. Barouch

~~Therapeutic efficacy of potent neutralizing HIV-1-specific monoclonal antibodies in SHIV-infected rhesus monkeys~~

Nature 503, 224–228 (14 November 2013)

Dan H. Barouch, James B. Whitney, Brian Moldt, Florian Klein, Thiago Y. Oliveira, Jinyan Liu, Kathryn E. Stephenson, Hui-Wen Chang, Karthik Shekhar, Sanjana Gupta, Joseph P. Nkolola, Michael S. Seaman, Kaitlin M. Smith, Erica N. Borducchi, Crystal Cabral, Jeffrey Y. Smith, Stephen Blackmore, Srisowmya Sanisetty, James R. Perry, Matthew Beck, Mark G. Lewis, William Rinaldi, Arup K. Chakraborty, Pascal Poignard, Michel C. Nussenzweig, et al.

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Recent Publications

WHITNEY LABORATORY